Redeemer’s University Achieves Landmark Success with First Human Genome Sequenced on Nigerian Soil

The Institute of Genomics and Global Health (IGH), formerly the African Centre of Excellence for Genomics of Infectious Diseases (ACEGID) at Redeemer’s University, has made history by successfully sequencing the entire human genome for the first time on Nigerian soil. This landmark achievement marks Africa’s first human genome sequenced using the cutting-edge Illumina NovaSeq™ X Plus sequencer.

This major milestone coincides with the official opening of the Genomics and Bioinformatics Training Academy at IGH, aimed at addressing the growing demand for skilled professionals in next-generation sequencing, bioinformatics, big data analytics, and artificial intelligence/machine learning applications. The facility is expected to significantly bolster the local workforce, providing essential training for managing high-tech wet labs and advancing genomic research.

While Africa is the birthplace of humanity and home to unparalleled genetic diversity, the continent has been underrepresented in genomic research, with less than 2% of human genomes sequenced and analyzed from African populations. The new NovaSeq™ X Plus sequencer, capable of processing more than 20,000 human genomes annually, will play a key role in changing this narrative, offering a level of output 2.5 times higher than the NovaSeq™ 6000.

Professor Christian Happi, Director of IGH, expressed the significance of the achievement, stating, "This successful sequencing is a major step towards understanding the genetic diversity and ancestry of African populations. This research will help address gaps in genomic knowledge, particularly those relating to African genetics."

The IGH has already sequenced and analyzed 11 diverse human samples on the NovaSeq™ X Plus, producing high-quality results from various African populations. These findings challenge historical biases in medical research, offering new avenues for more inclusive scientific inquiry.

In partnership with Illumina, the IGH also launched the Genomics Training Academy in 2023, a joint initiative designed to equip African scientists with the tools and knowledge necessary for cutting-edge genomic research. This partnership, along with the acquisition of the NovaSeq™ X Plus, positions IGH as a global leader in genomics research.

The success of this project promises to transform healthcare in Africa, enabling advancements in personalized medicine, precision therapies, and disease prevention. According to Dr. Happi, "This sequencing capacity opens the door to studying genetic factors tied to non-communicable diseases prevalent in African populations, ultimately paving the way for more targeted medical interventions."

With this achievement, Redeemer’s University and IGH are solidifying their position as key players in the global genomics landscape, driving forward innovation and personalized medicine on the African continent.