UNILAG Researchers Break Ground with Study on Neurological Effects of Long COVID in Nigeria

Two distinguished academics from the University of Lagos (UNILAG), Professor Njideka Okubadejo and Dr. Iorhen Akase, have achieved a research milestone with their groundbreaking study on the neurological manifestations of long COVID in Nigeria. The findings, published in the prestigious Journal of NeuroVirology, mark the first comprehensive exploration of neuro-long COVID in sub-Saharan Africa.

The study, conducted in collaboration with Northwestern University researchers led by Professor Igor J. Korlanik, was funded by the Robert J. Havey, MD Institute for Global Health Research Catalyzer at Northwestern University, Illinois, USA.

Key Findings:
The research analyzed data from 2,319 participants, yielding critical insights:

• Incidence of Neuro-Long COVID: 4.6% of participants reported neurological symptoms, with a significantly higher prevalence (11.5%) among previously hospitalized patients compared to those with mild cases (3.9%).
• Common Symptoms:
  • Memory problems/brain fog (59.4%)
  • Fatigue (55.7%)
  • Sleep disturbances (32%)
  • Headache (31%)
  • Numbness or pins and needles (11.3%)
  • Muscle pain (9.4%)
• Cognitive Impairment: Among those assessed, 16.9% displayed mild cognitive impairment.

The study highlights that many individuals continue to experience these symptoms up to two years post-recovery, underscoring the public health and socio-economic burden of long COVID.

Implications and Next Steps
Dr. Akase emphasized the importance of this research, stating:
"This study demonstrates that impactful research can be done in resource-limited settings, benefitting our communities and raising awareness of critical health challenges."

In response, UNILAG’s post-COVID clinic at the Lagos University Teaching Hospital (LUTH) is initiating rehabilitation programs to address these long-term effects. Future research will focus on targeted treatments for brain fog and cognitive dysfunction to improve patients’ quality of life and productivity.

A Call to Action
The findings call for urgent investment in screening, diagnosis, and clinical care for neuro-long COVID in Nigeria. This study reaffirms UNILAG’s commitment to innovative research and global health solutions, showcasing the resilience and excellence of Nigerian scientists in addressing pressing public health challenges.